Nonsteroidal Anti-Inflammatory Drugs and Risk of Melanoma
نویسندگان
چکیده
منابع مشابه
Nonsteroidal Anti-Inflammatory Drugs and Risk of Melanoma
Because nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit tumor growth in vitro, we investigated the association between NSAIDs and melanoma to determine if there was epidemiologic evidence of a chemopreventive effect from these medications. Three hundred twenty-seven subjects with incident melanoma and 119 melanoma-free controls completed a structured interview assessing melanoma risk fact...
متن کاملNonsteroidal anti-Inflammatory drugs and cardiovascular risk.
Nonsteroidal anti-inflammatory drugs (NSAID) inhibit cyclooxygenase (COX) enzymes, which exist in at least two isoforms, COX-1 and COX-2. Aspirin and older agents in this class are nonselective inhibitors of both COX-1 and COX-2. Newer agents termed "coxibs" are selective inhibitors of COX-2. Among the NSAID, only aspirin has been proven to significantly reduce cardiovascular risk, primarily th...
متن کاملNonsteroidal Anti-Inflammatory Drugs and Cardiovascular Risk
electivity toward cyclooxygenase (COX)-2 is usually dened by comparing the capacity of individual nonsteroidal nti-inflammatory drugs (NSAIDs) to inhibit in vitro or ex ivo the generation of thromboxane A2 (TXA2) through OX-1 in aggregating platelets with the capacity to inhibit rostaglandin (PG) E2 generation through COX-2, exressed in leukocytes after an inflammatory stimulus (1). his rather ...
متن کاملNonsteroidal anti-inflammatory drugs.
Non-steroidal anti-inflammatory drugs (NSAIDs) are usually defined as those agents that inhibit one or more reactions involved in the production of prostaglandins and thromboxanes, important mediators of the inflammatory process in many organs and tissues. They find use in horses in the supportive treatment of a variety of systemic states and painful musculoskeletal or soft tissue conditions. T...
متن کاملNonsteroidal Anti-Inflammatory Drugs, Gastroprotection, and Benefit–Risk
BACKGROUND Gastroprotective agents (GPA) substantially reduce morbidity and mortality with long-term nonsteroidal anti-inflammatory drugs (NSAIDs) and aspirin. OBJECTIVE To evaluate efficacy of NSAIDs, protection against NSAID-induced gastrointestinal harm, and balance of benefit and risk. METHODS Free text searches of PubMed (December 2012) supplemented with "related citation" and "cited b...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Skin Cancer
سال: 2011
ISSN: 2090-2905,2090-2913
DOI: 10.1155/2011/598571